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Rifaximin
  • CAS No.:

    80621-81-4
  • Molecular Formula:

    C43H51N3O11
  • Quality Standard:

    CP2010/EP8/In-house
  • Packing:

    25kg per fiber drum with inner PE bag
  • Mininmum Order:

    1kg
  • Technical Data Sheet: TDS Rifaximin .pdf

    Safety Date Sheet: MSDS Rifaximin .pdf

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  • Product Details
Rifaximin CAS 80621-81-4 is an orange powder and is soluble in ethanol, acetic acid, ethyl ester, chloroform and toluene but almost insoluble in water. Also, this drug is a kind of material that easily absorbs moisture. Rifaximin contains crystal form (EP Standard) and non-crystal form(CP Standard).

Specification 

CP Standard:

Characters                               Oange red or deep red crystalline powder. 

pH                                            4.5-7.5

The single impurity                   ≤1.0%

The total impurity                     ≤3.0%
Loss on drying                         ≤4.5%
Residue on ignition                  ≤0.1%
Heavy Metals                           ≤20ppm
Assay                                       ≥95.0%

EP Standard:

Appearance                             Red-orange,crystalline hygroscopic powder
Solubility                                 Practically insoluble in water,soluble in acetone and methanol
Assay                                      97.0 - 102.0%
Sum of impurities D and H       ≤0.5%
Unspecified impurities             ≤0.1%
Total impurity                          ≤1.0%
Water                                     ≤4.5%
Heavy Metals                          ≤20ppm
Sulphated Ash                        ≤0.1%
Residual solvents Ethanol      ≤0.5%

Application

Rifaximin, an antibiotic, is the derivatives from rifamycin and treatment for Gram-positive bacterium and negative bacteria, aerobic and anaerobic bacteria caused by acute or chronic intestinal infections. It is a kind of high-efficiency, intestinal tract antibiotics.

Rifaximin contains crystal form(EP Standard)and non-crystal form(CP Standard). Additionally, alpha-crystal form is the most important one of crystal froms which are widely used for the capsules production. Especially, alpha-crystal form can make the capsule more full compared with non-crystal form in the same weight of a capsule. That is to say, the untapped density of crystal form one is higher than the non-crystal form one.


Packing

25kgs in fiber drum with inner plastic bag, also can be packed according to clients' request.

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