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Polymyxin B Sulfate CAS 1405-20-5
  • CAS:

    1405-20-5
  • Molecular Formula:

    C48H84N16O17S
  • Quality Standard:

    99%
  • Packing:

    25 kgs/ fiber drum
  • Mininmum Order:

    25KG
  • Price inquiry:

    sales@tnjchem.com
  • Manufacturer:

    TNJ Chemical

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  • Product Details

Buy Polymyxin B Sulfate CAS 1405-20-5, a chemical intermediate for the infection and inflammation caused by sensitive bacteria and Pseudomonas aeruginosa from TNJ Chemical, China leading Polymyxin B Sulfate suppliers & manufacturers. If you want to buy polymyxin B standard solution , please mail to sales@tnjchem.com

 

Polymyxin B Sulfate is a white or almost white powder, the efficacy ingredient is polymyxin B sulfate. Clinically, it is mainly used for infection and inflammation caused by sensitive bacteria and Pseudomonas aeruginosa.


Specification
TESTS                                                    SPECIFICATIONS
Description                                            White or almost white powder
Identification                                         Conforms to standard
Specific optical rotation                         -78°~-90°
PH(2%)                                                  5.0~7.0
PH(0.5%)                                               5.0~7.5
Loss on drying                                       ≤6.0%
Phenylalanine                                        9.0~12.0%
Related substances(HPLC)                    Major impurity≤3.0%
                                                              Sum of impurity≤17.0%
                                                              Sulphate ash ≤0.75%
                                                              Suphate 15.5~17.5%
Heavy metals                                         ≤20ppm
Potency(on the dried basis)                   ≥6500IU/mg
Assay(HPLC,on the dried basis)             Sum of polymyxin B1,B2,B3 and B1-1≥80%
                                                               Polymyxin B3≤6.0%
                                                               Polymyxin B1-1≤15%

Application

-To reduce the development of drug-resistant bacteria and maintain the effectiveness of polymyxin B and other

antibacterial drugs, polymyxin B should be used only to treat or prevent infections that are proven or strongly

suspected to be caused by bacteria. 

-Polymyxin B sulfate is the sulfate salt of Polymyxins B1 and B2, which are produced by the growth of Bacillus

polymyxa (Prazmowski) Migula (Fam. Bacillacea). It has a potency of not less than 6500 polymyxin B units per mg,
calculated on the anhydrous basis. Polymyxin B sulfate has a bactericidal action against almost all gram-negative

bacilli except the Proteus group. 

-Polymyxin B sulfate is a drug of choice in the treatment of infections of the urinary tract, meninges, and

bloodstream caused by susceptible strains of Ps. aeruginosa. It may also be used topically and subconjunctivally
in the treatment of infections of the eye caused by susceptible strains of Ps. aeruginosa.

Packing

25 kgs/ fiber drum


Storage

Store in dry, dark and ventilated place.

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