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Diphenhydramine Base is a first-generation antihistamine possessing anticholinergic, antitussive, antiemetic, and sedative properties that is mainly used to treat allergies. It is also used in the management of drug-induced parkinsonism and other extrapyramidal symptoms. The drug has a strong hypnotic effect and is FDA-approved as a non-prescription sleep aid, especially in the form of diphenhydramine citrate.
Specification
Melting point 167-172°C
Boiling point bp2.0 150-165°
Density 0.9889 (rough estimate)
Refractive index 1.5450 to 1.5490
Acidity coefficient (pKa) pKa 9.1 (Uncertain)
Color White crystalline powder
Purity 99%Application
The product forms a salt with hydrochloric acid to make diphenhydramine hydrochloride, which is one of the antihistamine drugs listed in the "National Essential Medicines". It can reduce the reaction of tissues to the body, eliminate various allergic symptoms, has strong central nervous system inhibition for Chemicalbook and mild sedation and antiemetic effects. For urticaria, hay fever, angioedema, serum sickness, contact dermatitis, allergic conjunctivitis. It can prevent motion sickness, such as seasickness, motion sickness, vomiting during pregnancy and paralysis tremor.
25 kg/fiber drum