Basic product information of Polyquaternium-1 CAS 75345-27-6 (PQ-1)
Product name: Polyquaternium-1
Common alias: Polychloroammonium chloride PQ-1、Polyquad
English name: Polyquaternium-1/Polidronium Chloride
CAS No.：75345-27-6
Molecular formula: C22H48Cl3N3O6
Molecular weight: 556.99
Physical and chemical characteristics
Appearance: Amber to dark brown viscous solid/high viscosity aqueous solution; Industrial products are often supplied as concentrated aqueous solutionsMoisture absorption: Highly hygroscopic, quickly absorbs water and softens upon exposure to air
Solubility: easily soluble in water; Insoluble in organic solvents such as ethanol, acetone, and ether
PH characteristics: The pH value of a 1% aqueous solution is approximately 5.0-7.0
Stability: Stable sealing at room temperature; Avoid strong alkalis and high concentration oxidants; Heating at high temperature for a long time will slow down the degradation and decrease the antibacterial activity
Safety features: low irritation cationic polymer; Eye grade specification with extremely low irritation
Main use
Core preservatives for ophthalmic preparations (most mainstream use)
Global classic eye drops and contact lens care solution specialized antibacterial agents; Inhibiting bacteria and fungi, compared to benzalkonium chloride, it has less irritation to the ocular mucosa and is widely used in artificial tears and soft contact lens care solutions.
Daily chemical cleaning and care raw materials
Skin care essence, mouthwash and oral care products are used as mild antibacterial preservative and film forming conditioner; Can improve the smoothness of the skin/hair surface.
Pharmaceutical external preparations
Skin cleansing solution and wound care solution for antibacterial and anti-corrosion purposes.
Fine Industry
Water based antibacterial and cationic conditioning agents.Antibacterial spectrum: It has inhibitory effects on Gram positive bacteria, Gram negative bacteria, some yeast, and mold.
Reference quality indicators (COA standard for pharmaceutical/ophthalmic grade foreign trade)
| Appearance | Amber to dark brown viscous solid / liquid |
| Active Content | ≥95.0%（solid）；34~40%（water solution） |
| pH (1% aqueous solution) | 5.0 ~ 7.0 |
| Heavy Metals (Lead) | ≤10 ppm |
| Arsenic | ≤2 ppm |
| Loss on drying | ≤8.0 % |
| Microbial Limit | Total Aerobic Count ≤100 CFU/g No Salmonella, E.Coli, Pathogens |
Standard foreign trade packaging
25kg plastic drum/lined with PE inner membrane drum;
Sample packaging: 1kg, 5kg food grade plastic pots;Identification label: Product name Polyquaternium-1, CAS75345-27-6, batch, moisture-proof label.
Storage and transportation requirements
Store in a cool, dry, and ventilated warehouse, with a recommended ambient temperature of ≤ 25 ℃;
The container is strictly sealed to prevent moisture absorption and water vapor from entering; Stay away from strong alkalis and highly oxidizing chemicals;
Store in a dark place and avoid long-term direct sunlight; Shelf life: 24 months under sealed conditions.
Key points of transportation
Ordinary general cargo, not classified as hazardous chemicals;
Prevent packaging damage, rain and water ingress during transportation;It is prohibited to mix and transport with strong alkali and bleaching oxidants in the same vehicle.
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