‑ Chemical Name: (R)-(+)-2,4‑Dihydroxy‑N‑(3‑hydroxypropyl)‑3,3‑dimethylbutanamide
‑ INCI Name: Panthenol (D‑Panthenol)
‑ EINECS No.: 201‑327‑3
‑ Synonyms: Dexpanthenol, D‑Pantothenyl alcohol, Provitamin B5 (biologically active form)
‑ Molecular Formula: C₉H₁₉NO₄
‑ Molecular Weight: 205.25 g/mol
‑ Note: D‑Panthenol is biologically active; DL‑Panthenol (CAS 16485‑10‑2) is racemic mixture.
- D-panthenol 75%：Aqueous solution（75% D‑Panthenol + 25% water）；
- D-panthenol 98%：Undiluted pure liquid，complies with USP‑NF standard
Chemphysical properties
Appearance @25℃ Colorless to slight‑yellow clear viscous hygroscopic liquid; may crystallize upon long‑term storage
Odor Almost odorlessDensity @20℃ 1.20 g/cm³
Refractive index (20℃) 1.495‑1.502
Specific Optical Rotation [α]₂₀ᴰ +29.0° ~ +31.5°Solubility Freely soluble in water, ethanol, propylene glycol; insoluble in mineral oil & vegetable oil
pH (10 % aqueous solution) 6.0‑8.0
Hygroscopicity Strongly hygroscopicStability Stable under normal conditions; avoid strong acid / strong alkali high‑temperature heating
Quality specification (USP & cosmetic grade, 98%)
| Test Item | Specification |
|---|---|
| Assay | 98.0‑102.0 % |
| Specific Optical Rotation | +29.0° ~ +31.5° |
| Refractive index (20℃) | 1.495‑1.502 |
| Water content | ≤1.0 % |
| 3‑Aminopropanol | ≤0.1 % |
| Residue on ignition | ≤0.1 % |
| Heavy Metals (Pb) | ≤10 ppm |
| Arsenic | ≤2 ppm |
Application & Use
‑ High‑activity humectant & repairing agent for cosmetic formulations. Far higher biological activity than DL‑Panthenol.
‑ Skincare: enhance skin barrier, soothe irritated skin, reduce redness; widely used in toner, serum, cream, lotion, after‑sun care, mask.
‑ Hair care: improve hair moisture, gloss and elasticity, reduce split‑ends; added in shampoo, conditioner, hair mask.
‑ Also used in pharmaceutical ointments, oral‑care products.
‑ Recommended dosage: 0.5‑5.0 % for cosmetic formulas.
Packing
‑ 25 kg PE plastic drum
‑ Small packing: 1 kg / 5 kg aluminium foil bottle
‑ Palletized for sea shipment
Transportation & Storage
‑ Store in cool, dry, well‑ventilated warehouse, keep tightly sealed.
‑ Strictly prevent moisture absorption; avoid direct sunlight and high temperature.
‑ Shelf‑life: 24 months under unopened recommended storage.
‑ Transport as general cosmetic & pharmaceutical raw material, non‑dangerous goods.
‑ Avoid skin & eye contact.
- Disclaimer: Above are typical values, not contractual standards. Final data subject to batch‑wise COA.
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