Product name: Tranexamic Acid
CAS‑No：1197‑18‑8
IUPAC Name: trans‑4‑(Aminomethyl)cyclohexanecarboxylic acidSynonym: TXA
EC‑No: 214‑818‑2
Molecular Formula: C8H15NO2Molecular Weight: 157.21 g/mol
Brief Introduction
Tranexamic Acid is a synthetic lysine‑derived antifibrinolytic compound. It appears as white crystalline powder, odourless. Freely soluble in water, practically insoluble in ethanol and acetone. It inhibits plasminogen activation to prevent fibrin clot degradation. It is widely applied as pharmaceutical API for hemostatic purpose, and also popular functional raw material in cosmetic formulations for brightening and improving hyper‑pigmentation issues.
Specification
| Test Item | Specification | Test Result | Test Method |
|---|---|---|---|
| Appearance | White crystalline powder | White crystalline powder | Visual |
| Assay (on dried basis) | 99.0‑101.0 % | 99.52 % | Titration |
| Identification | IR spectrum conforms | Complies | IR |
| Loss on Drying | ≤ 0.5 % | 0.41 % | Vacuum drying |
| Residue on Ignition | ≤ 0.1 % | 0.06 % | Ignition gravimetry |
| Chloride (Cl) | ≤ 0.014 % | <0.014 % | Titration |
| Sulfate (SO₄) | ≤ 0.014 % | <0.014 % | Titration |
| Heavy Metals (Pb) | ≤10 ppm | <10 ppm | AAS |
| Total Related Substances | ≤0.20 % | 0.12 % | HPLC |
| pH (10% aqueous solution) | 7.0‑8.0 | 7.45 | pH‑meter |
Typical Physical‑Chemical Properties
Melting point: >300 ℃ (decomposition)
pH (10% water solution): 7.0‑8.0
Solubility: Soluble in water; insoluble in alcohol & oil
Stability: Stable under normal conditions; protect from strong light and moisture
Applications
Pharmaceutical API: Antifibrinolytic hemostatic drug for surgical bleeding, trauma hemorrhage, gynecological bleeding and menorrhagia.
Cosmetic raw material: Skin‑brightening ingredient, reduces melanin generation, improves melasma and post‑inflammatory pigmentation in serums, creams and lotions.
Packaging & Storage
HS Code: 2922499990
UN Classification: Non‑dangerous goods
Package: 25 kg fiber drum with inner PE liner
Storage: Keep container tightly sealed, store in cool, dry, well‑ventilated warehouse, avoid direct sunlight and dampness.
Shelf‑life: 36 months under recommended storage.
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