Product name: Calcium/Sodium PVM/MA Copolymer
CAS‑No：62386-95-2
EC Number：613‑024‑7UNII：5216H1HX5F
Product Identification
Chemical Name: 2‑Butenedioic acid (2Z)‑, polymer with methoxyethene, calcium sodium salt
Synonym: Poly(methyl vinyl ether‑co‑maleic acid) calcium‑sodium mixed salt
Polymer structure: Alternating 1:1 methyl vinyl ether / maleic acid copolymer, partial Ca/Na ionic cross‑linking
Appearance: White to off‑white free‑flowing powder
Molecular formula: (C₃H₆O‑C₄H₄O₄)ₙ · Caₓ · NaᵧGrade: Oral‑care / Pharmaceutical excipient grade
Physical & Chemical Properties
Solubility: Water‑swellable, slowly hydrate in water to form high‑viscosity muco‑adhesive gel; Insoluble in ethanol, acetone, hydrocarbons
Viscosity behavior: Viscosity rises upon hydration; high electrolyte may cause precipitationOptimum working pH: 4.0‑8.5 for maximum bio‑adhesion & film performance
Thermal stability: Stable under normal processing temperature; avoid over‑heating >150 ℃
Film property: Forms flexible, transparent continuous film after hydration
Bio‑adhesion: Strong muco‑adhesive to oral mucosa, denture surface by calcium ionic bridge effect
Typical Specification
| Test Item | Specification | Test Method |
|---|---|---|
| Appearance @25℃ | White‑off‑white powder | Visual |
| Moisture (KF) | 6.0‑15.0 % | Karl‑FischerAlibaba.co... |
| pH (1 % aqueous solution) | 5.5‑7.0 | Potentiometricyrchemspec... |
| Calcium content (anhydrous basis) | 11.0‑15.0 % | Titrationyrchemspec... |
| Tap density | ≥0.50 g/cm³ | Tap density testeryrchemspec... |
| Particle size (pass 200 mesh) | ≥85 % | Sieve analysis |
| Heavy metals | ≤7 ppm | AASyrchemspec... |
| Total aerobic microbial count | ＜500 CFU/g | Pharmacopoeia method |
Function & Application
Denture adhesive：core bio‑adhesive raw material for denture cream / powder, provide long‑lasting wet bonding strength, block food debris infiltration
Oral care：oral mucosal patch, mouth‑ulcer dressing, thickener & adhesive in toothpaste
Pharmaceutical excipient：muco‑adhesive carrier for buccal / nasal sustained‑release formulations
Cosmetic：film‑former, viscosity regulator for oral cosmetic products
Formulation note: Add slowly under high‑speed agitation to prevent lump formation; do not co‑add with high‑concentration strong electrolyte.
Handling, Storage & Packaging
Packaging：25 kg fiber drum with inner PE liner
Storage condition：Store in cool, dry, well‑ventilated warehouse, seal tightly, avoid moisture absorption
Shelf‑life：12 months under original sealed package
Handling precaution：Avoid dust inhalation; wear dust mask when powder transferring
Regulatory Status
Non‑CMR, Non‑PFAS, Non‑nano substanceListed on TSCA, KECL, CIR approved for oral cosmetic usage
Compliant for pharmaceutical oral‑mucus excipient application
Not dangerous goods for transportation
Disclaimer: All data are typical values for reference only, not contract specifications. Final specification refer to Certificate of Analysis per batch.
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