Nicotinamide (CAS 98-92-0), also called niacinamide, is a water‑soluble vitamin B3 derivative. It is white crystalline powder with good stability, widely utilized in feed, cosmetics, pharmaceutical and food nutrition fields for skin‑care and nutritional supplementation. TNJ Chemical is the key manufacturer and exporter of Nicotinamide since from 2001. If you want to buy high quality Nicotinamide at competitive price from China, please contact sales@tnjchem.com
Product information
Chemical Name Nicotinamide / Niacinamide
Synonym 3‑Pyridinecarboxamide
CAS No. 98-92-0
Molecular Formula C₆H₆N₂O
Molecular Weight 122.13Appearance White crystalline powder
Chemphysical properties
Melting Point 128-131 ℃
Solubility Freely soluble in water and ethanol; slightly soluble in ether
pH (10% aqueous solution) 5.5-7.5Stability Stable under ordinary conditions
Quality specification
| Test Item | USP / EP Pharma Grade | Cosmetic Grade | Food Grade | Feed Grade |
|---|---|---|---|---|
| Appearance | White crystalline powder | White crystalline powder, low color | White crystalline powder | White crystalline powder |
| Assay (dry basis) | 98.5‑101.5 % | ≥99.0 % | ≥98.5 % | ≥98.0 % |
| Loss on Drying | ≤0.5 % | ≤0.5 % | ≤0.5 % | ≤0.5 % |
| Residue on Ignition | ≤0.1 % | ≤0.1 % | ≤0.1 % | ≤0.1 % |
| Heavy metals (Pb) | ≤10 ppm | ≤10‑20 ppm | ≤20 ppm | ≤20 ppm |
| Nicotinic Acid (key cosmetic impurity) | ≤2000 ppm (USP general limit) | ≤50‑100 ppm (low‑irritation requirement) | ‑ | ‑ |
| Melting range | 128‑131 ℃ | 128‑131 ℃ | 128‑131 ℃ | 128‑131 ℃ |
| pH (10 % aqueous) | 5.5‑7.5 | 5.5‑7.5 | 5.5‑7.5 | 5.5‑7.5 |
| Microbial control | Pharma microbial limits | Cosmetic microbial limits | Food microbial limits | Feed hygiene standard |
| Main Standard | USP‑NF, Ph.Eur. | Internal cosmetic raw‑material spec | FCC / national food additive standard | GB feed additive standard |
| Typical Application | oral drugs, topical pharma preparations, dietary supplements | serum, cream, mask, skincare cosmetic formulas | food fortification, health supplements | animal feed additive |
Key Notes
Cosmetic critical index: Nicotinic acid (niacin) impurity causes skin stinging / flushing; cosmetic grade strictly controls this parameter, while standard USP grade does not set tight limit for nicotinic acid.
Cross‑over grade: Many suppliers supply USP-compliant material for cosmetic use, but check nicotinic acid value before cosmetic formulation.
Special cosmetic sub‑grade: Micronized nicotinamide, finer particle size for transparent serum & ampoule production.
Feed grade is not allowed for human cosmetic / food usage.
Application & use
Cosmetics: Multi-functional skincare raw material; inhibits melanin transfer, repairs skin barrier, reduces skin irritation. Used in serum, cream, lotion, mask, ampoule.
Pharmaceutical & Dietary supplement: Vitamin B3 source, for pellagra prevention, oral & topical dermatological preparations.
Food industry: Nutritional fortifier for beverages, functional food and health products.
Feed: Nutritional additive for animal feed.Packing, transportation & storage
Packing: 25 kg paper drum with inner PE bag; custom packaging acceptable.
Transportation: General cargo; keep away from moisture and direct sunlight.
Storage: Store in cool, dry, well-ventilated place, keep container tightly closed.
Shelf life: 24 months under recommended storage.
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