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Magnesium orotate, the magnesium salt of orotic acid, is a mineral supplement. It can be used in treating extracellular magnesium deficiency, as well as in mitigating magnesium depletion that inhibits the binding of adenosine triphosphate via orotic acid, which provides binding sites.

1) Supports Cardiovascular Health
Studies show that orotic acid salts, magnesium salts to be specific, supports the heart. One study also showed that magnesium orotate may be beneficial to those who have suffered from heart failure.

2) Boosts Stamina and Endurance
Animal and human research has shown that magnesium orotate may be effective for increasing endurance and exercise tolerance. These effects were especially noted in patients who previously suffered from cardiovascular issues. Trained athletes have also shown endurance-supportive effects following magnesium orotate supplementation.

3) Provides GI Support
One study focused on children suffering from constipation found that magnesium orotate was effective for relieving symptoms. This doesn't come as any surprise to most physicians, as magnesium is known to be a natural laxative. The benefits of magnesium orotate on other gastrointestinal conditions, like irritable bowel syndrome, have yet to be determined. Future research is needed to determine its role in the support of the GI system.