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Chlorobutanol (CAS No 57-15-8), or trichloro-2-methyl-2-propanol, is a chemical preservative, sedative, hypnotic and weak local anaesthetic similar in nature to chloral hydrate. It has antibacterial and antifungal properties. Chlorobutanol is typically used at a concentration of 0.5% where it lends long term stability to multi-ingredient formulations. However, it retains antimicrobial activity at 0.05% in water. In pure state it is a white, volatile solid with a menthol-like odor.
Characteristics White crystalline; a little like camphor's smelly; easy volatile.
Easily dissoved in ethanol, chloroform, either or naphtha; micro dissolved in water.
Melting point ≥77℃
Acidity Compare with color blue, not darker
Clarity 2 turbidity standard
Residue on ignition ≤0.1%
Used as preservatives for biological fluids, for alkaloid solutions, plasticizers for cellulose esters and ethers.
Stored in cool and dry place. Keep away from strong light and heat.