2-Methyl-1,4-naphthoquinone CAS 58-27-5, also known as Menadione or Vitamin K3, is a synthetic yellow crystalline naphthoquinone compound. It exhibits provitamin K activity, sensitive to light and easy to oxidize. It is widely applied in animal feed nutrition, pharmaceutical intermediate and biochemical research. TNJ Chemical is the leading manufacturer and exporter since from 2001. We guarantee high quality, competitive price, stable supply, fast delivery and tech support etc. To find more, please contact sales@tnjchem.com
Product Information

Chemical Name 2-Methyl-1,4-naphthoquinone
CAS No. 58-27-5
EINECS 200-372-6
Molecular Formula C₁₁H₈O₂
Molecular Weight 172.18
Synonym Menadione, Vitamin K3, Menaphthone, 2-methylnaphthalene-1,4-dione
Chemphysical Properties
Appearance Bright yellow crystalline powder
Melting Point 105–107 ℃
Odor Almost odorless
Solubility Insoluble in water; soluble in ethanol, benzene, chloroform, vegetable oil
Stability Light sensitive; easily decomposed under strong alkali and reducing environment
Quality Specification
| Test Item | Feed Grade | USP / Pharma Grade |
|---|---|---|
| Assay | ≥98.0% | ≥99.0% |
| Loss on drying | ≤0.5% | ≤0.3% |
| Residue on ignition | ≤0.1% | ≤0.05% |
| Heavy metals (as Pb) | ≤20 ppm | ≤10 ppm |
| Arsenic (As) | ≤3 ppm | ≤1 ppm |
| Identification | Conforms | Conforms |
Use & Application
Feed grade 2-Methyl-1,4-naphthoquinone serves as vitamin K3 source for animal feed premix. It promotes blood clotting function of livestock, poultry and aquatic animals, prevents hemorrhage disease and improves bone health. It is commonly formulated into feed additive premix, and can be converted into water-soluble menadione sodium bisulfite derivative for feed application.
USP / Pharma grade 2-Methyl-1,4-naphthoquinone is used as pharmaceutical intermediate and biochemical research reagent. It acts as precursor for vitamin K related active ingredients, and used in lab redox reaction studies, cell culture and biological mechanism research. Strict impurity control meets pharmacopoeia requirement for pharma raw material production and laboratory analytical work.
Packing
25kg fiber drum with PE inner bag. Small packing 1kg /5kg aluminum foil bag available.
Delivery & Storage
Store in cool, dry, dark and ventilated warehouse. Keep tightly sealed, protect from light, heat and oxidizing agents. Avoid contact with alkaline and reducing substances. Shelf life is 24 months under proper storage.



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