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Atorvastatin calcium suppliers, factory, manufacturers
Atorvastatin calcium suppliers
  • CAS No.:

    134523-03-8
  • Molecular Formula:

    C66H68CaF2N4O10
  • Quality Standard:

    98.0%Min
  • Packing:

    25 kg/drum
  • Mininmum Order:

    1 kg

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  • Product Details

Find Atorvastatin calcium suppliers from China, and select TNJ Chemical as the top Atorvastatin calcium suppliers, factory and manufacturers. We offer best price of Atorvastatin calcium with high quality. If you want to buy Atorvastatin calcium, please feel free to contact [email protected]

 

Atorvastatin calcium (CSA No 134523-03-8) is marketed under the trade name Lipitor among others, is a member of the drug class known as statins, which are used primarily as a lipid-lowering agent and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.

Atorvastatin was first made in August 1985 at Warner-Lambert's Parke-Davis research facility in Ann Arbor, Michigan by a team led by Bruce Roth. From 1996 to 2012 under the trade name Lipitor, atorvastatin became the world's best-selling drug to that point, with more than US$125 billion in sales over approximately 14.5 years. In the UK atorvastatin costs about 2 pounds per month as of 2016.


Specification

Appearance                                 White or almost white powder

Identification                                 IR, calcium

WATER                                         3.5-5.5%

Heavy metals                                 NMT20ppm

Assay                                         98.0%-102%(calculated to anhydrous substances)

Enantiomer atorvastatin calcium         NMT0.3%

Impurity A                                        NMT0.3%

Impurity B                                        NMT0.3%

Impurity C                                         NMT0.3%

Impurity D                                 NMT0.1%

Unspecfied impurity                         NMT0.1%

Total                                                 NMT1.0%

Ethanol                                         NMT5000ppm

Toluene                                         NMT890ppm

Hexane                                         NMT290ppm

Total aerobic miorobial count         NMT1000CFU/g

Total combined mold and yeast count NMT100CFU/g

Eschericha coli                                 Negative


Application

Atorvastatin Calcium, used for lowering blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammation and other mechanisms. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.


Packing&Storage

25 kg/drum.

Stored in dry and cool place.

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