Basic Information of Diazolidinyl Urea CAS 78491-02-8
Chinese name: Bis (hydroxymethyl) imidazolidinylurea, also known as diazoalkylurea, Germall II, Germall II
English name: Diazolinyl UreaCAS number: 78491-02-8
EINECS:278‑928‑2
Molecular formula: C8H14N4O7
Molecular weight: 278.22
Physicochemical properties
Appearance: White free flowing powder, hygroscopic, with slight characteristic odor
Solubility: Easily soluble in water, glycerol, and propylene glycol; Insoluble in ethanolPH (1% aqueous solution): 6.0-8.0
Using pH range: 3-9, stable under wide pH conditions
Type: Formaldehyde releasing broad-spectrum cosmetic preservative, slowly releasing trace amounts of formaldehyde to inhibit microorganisms, effective against bacteria, mold, yeast, especially Pseudomonas aeruginosa
Typical indicators of cosmetic grade
| Item | Specification |
| Appearance | White flowing powder |
| total nitrogen content,% | 19.0-21.5 |
| drying loss,% | ≤ 3.0 |
| burning residue,% | ≤ 3.0 |
| heavy metal (Pb), ppm | ≤ 10 |
| arsenic (As), ppm | ≤ 3 |
| Recommended addition amount | 0.1-0.4% |
Main applications
Cosmetic preservatives: cream, lotion, shampoo, conditioner, shower gel, facial mask, wet towel and other resident&washaway skin care products; Often used in combination with nipagin ester to improve the efficiency of the anti-corrosion system.Broad spectrum antibacterial: Inhibits Gram positive and Gram negative bacteria, yeast, and mold.
Attention: It belongs to formaldehyde releasing preservatives, and there is a risk of sensitization in some populations due to contact; Domestic cosmetics regulations limit the control of formaldehyde emissions.
Safety and storage and transportation
Avoid inhaling dust and prevent contact with eyes; There is a possibility of sensitization to some skin.
Packaging: 25kg cardboard drum.Storage: Sealed, cool, dry, ventilated, moisture-proof and moisture absorbing; Stay away from strong oxidants.



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