Diazolidinyl urea CAS 78491-02-8, is a broad-spectrum cosmetic preservative. It is a formaldehyde-releasing antimicrobial agent, effective against bacteria, yeast and molds, especially strong inhibition for Pseudomonas. It features good compatibility with surfactants and most cosmetic raw materials, widely used in water-based personal care formulations. We also have liquid Jiemorel Plus. TNJ Chemical is the leading manufacturer and exporter since from 2001. We guarantee high quality, competitive price, stable supply, fast delivery and tech support etc. To find more, please contact sales@tnjchem.com
Product Information of Diazolidinyl Urea
Product Name Diazolidinyl Urea
CAS No. 78491-02-8
INCI Name Diazolidinyl UreaSynonym 1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea
EINECS 278-928-2
Molecular Formula C₈H₁₄N₄O₇Molecular Weight 278.22
Jiemorel Plus: Jiemorel Plus is a broad-spectrum liquid cosmetic preservative blend composed of Diazolidinyl Urea, Iodopropynyl Butylcarbamate (IPBC) and Propylene Glycol. It delivers synergistic antimicrobial effect against bacteria, yeast and mold, compatible with surfactants, proteins and most cosmetic raw materials, suitable for both leave-on and rinse-off personal care formulations. CAS No. 57-55-6 (Propylene Glycol); 78491-02-8 (Diazolidinyl Urea); 55406-53-6 (IPBC), Composition (Diazolidinyl Urea, IPBC, 1,2-Propanediol)
Chemphysical Properties of Diazolidinyl Urea
Appearance White or off-white free-flowing crystalline powder
Odor Slight characteristic odor
Melting Range 157–160℃
Solubility Freely soluble in water, soluble in glycerin; insoluble in mineral oil and vegetable oil
pH (1% aqueous solution) 6.0 – 8.0
Stability Stable under normal cosmetic formulation conditions; avoid strong alkaline and high temperature over 80℃
Quality Specification of Diazolidinyl Urea
| Test Item | Spec |
|---|---|
| Assay (Nitrogen Calculation), % | ≥98.0 |
| Nitrogen Content, % | 19.0 – 21.0 |
| Loss on Drying, % | ≤3.0 |
| Residue on Ignition, % | ≤0.5 |
| Heavy Metal (Pb) | ≤10 ppm |
| Formaldehyde Release Content | Compliant with cosmetic regulation |
Specification of Jiemorel Plus liquid
| Test Item | Spec |
|---|---|
| Nitrogen Content, % | 7.5 – 8.5 |
| IPBC Content, % | 0.65 – 0.95 |
| Residue on Ignition, % | ≤1.5 |
| Heavy Metal (Pb) | ≤10 ppm |
Use & Application
Cosmetic grade diazolidinyl urea is widely used as preservative in leave-on and rinse-off personal care products, including creams, lotions, shampoos, body wash, facial cleansers, wet wipes and hair styling products. It suppresses the growth of bacteria, yeast and mold in aqueous cosmetic systems, prevents product spoilage during storage and use. It shows outstanding performance against pseudomonas, which is a common contaminant in cosmetic raw materials.
Industrial grade diazolidinyl urea can be used as biocide for water-based emulsions, water-soluble additives and some water-based polymer formulations to control microbial contamination and odor generation.
It is usually used alone or combined with other preservatives such as parabens and iodopropynyl butylcarbamate to build a composite preservative system and broaden antimicrobial spectrum.
Packing
25kg fiber drum with inner PE liner.
Delivery & Storage
Store in tightly sealed containers in cool, dry and ventilated warehouse. Keep away from direct sunlight, heat source and high temperature environment. Do not mix with strong alkaline materials. Shelf life is 24 months under proper storage.



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