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38083-17-9;Climbazole
Climbazole 99.5% CAS 38083-17-9 Cosmetic anti‑dandruff preservative
  • CAS:

    38083-17-9
  • Molecular Formula:

    C15H17ClN2O2
  • Quality Standard:

    Cosmetic grade USP
  • Packing:

    25kg/fibre drum or as request
  • Factory Site:

    Anhui, China
  • Mininmum Order:

    25kg
  • Price inquiry:

    sales@tnjchem.com
  • Manufacturer:

    TNJ Chemical

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  • Product Details
Climbazole (CAS 38083-17-9, also known as Ganbaosu) is imidazole-based broad-spectrum antifungal active cosmetic raw material. It exhibits strong inhibitory effect against Malassezia, the main fungus causing dandruff and scalp itching. It is stable in wide pH range, compatible with most cosmetic surfactants, used for anti‑dandruff shampoo, hair conditioner, scalp care lotion, body wash and cosmetic preservative booster. Available in Cosmetic Grade. TNJ Chemical is a professional manufacturer and exporter since 2001. We guarantee high-quality products, competitive prices and thoughtful service. If you want to buy or have any other inquiries, please contact sales@tnjchem.com

General Product Data

Product Name Climbazole

CAS Number 38083-17-9

EINECS‑EC 253-775-4

Synonyms 1-(4-Chlorophenoxy)-3,3-dimethyl‑1‑(imidazol-1-yl)-2-butanone; Ganbaosu

Molecular Formula C15H17ClN2O2

Molecular Weight 292.76 g/mol

Chemical Family Imidazole-derived antifungal cosmetic active ingredient

Available Grade Cosmetic Grade

Regulatory Status REACH registered; Non-CMR, Non-PFAS, Non-nano; Complies with cosmetic regulation limits


Physical & Chemical Characteristics

Physical form White to off-white crystalline powder

Odour Faint characteristic odour

Melting Point 94-98 °C

Density (20 °C) 1.20 g/cm³

Solubility in water Practically insoluble

Solubility Soluble in ethanol, methanol, isopropanol and polar organic solvents

pH scope of stability pH 4-8, stable under acidic and weak‑alkaline cosmetic formulation conditions

Bulk density 420-580 kg/m³

Processing hint Heat-stable; avoid strong oxidizing agents. Dissolve in alcohol prior to adding into aqueous cosmetic systems.

 

Quality Requirements

Test Parameter Cosmetic Grade Test Method
Assay (HPLC) ≥99.0 % High‑Performance Liquid Chromatography
Appearance White to off‑white crystalline powder Visual inspection
Melting Point 94‑98 °C Capillary melting‑point apparatus
Loss on Drying ≤0.50 % Vacuum gravimetry
Sulphated Ash ≤0.20 % Gravimetry
p‑Chlorophenol impurity ≤150 ppm HPLC
Heavy Metals (as Pb) ≤10 ppm AAS

 

Main Functions & Recommended Applications

Anti-dandruff hair-care: Key active ingredient for anti-dandruff shampoo, rinse‑off conditioner, scalp treatment lotion, inhibits Malassezia to reduce dandruff and scalp itch.

Leave-on hair care: Hair tonic, scalp serum for long-term scalp conditioning.

Body-care products: Anti-fungal additive for body wash and soap formulations.

Cosmetic preservative booster: Enhance anti‑microbial performance of creams and lotions.


Important note:

Climbazole is almost insoluble in water; pre-dissolution in ethanol or glycol is required before compounding cosmetic formulations. Do not exceed regulatory maximum permitted dosage in finished cosmetics. End-user shall validate suitability for own formulation and final application. Refer to SDS for full safety guidance.

 

Logistics & Storage Information

Packaging options: 25 kg fibre-drum with inner PE liner; or as per request.

Lead-time: Samples: 7-15 working days against deposit. 

Storage condition: Keep container tightly closed. Store in cool, dry, well-ventilated warehouse, keep away from heat source, alkali and oxidizing agents. Protect from direct sunlight.

Shelf-life: 24 months under original sealed storage.
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