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Loratadine CAS 79794-75-5 is a commonly used anti-allergic drug and belongs to the second generation of long-acting tricyclic antihistamines. It has a rapid onset of action, a strong effect, and does not contain hormones. By inhibiting histamine H1 receptor competitively, allergic symptoms caused by histamine are inhibited without significant anticholinergic and central inhibitory effects.
Appearance White or almost white powder
Purity, % ≥99.00
Molecular Weight 382.88
Melting point 134-136°C
Storage condition 2-8°C
Water solublity It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol.
Stablity Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.
Used as anti-histamine drugs, have a high selectivity for the peripheral nerve H1 receptors and have a strong effect and a long time. For allergic arthritis, allergic rhinitis.
25kg per fiber drum, 9 tons per 20'ft
Storage & Handling
Store in a dry, cool, well-ventilated area away from heat ,open flames, organic chemicals, oxidants and light.
Always refer to the Material Safety Data Sheet (MSDS) for detailed information on handling and disposal.