Product name: Alpha-GPC 99% (L-α-Glycerylphosphorylcholine 99%)
CAS No.: 28319-77-9
Chemical Name: L-α-Glycerylphosphorylcholine
Synonyms: Choline Alfoscerate, sn-Glycero-3-phosphocholine, Alpha-GPC
Molecular Formula: C₈H₂₀NO₆P
Molecular Weight: 257.22
EINECS No.: 248-962-2Grade: Pharma / High Purity Food Grade (No mannitol or other excipients, pure crystalline powder)
1. Chemphysical Properties
Appearance White to off-white crystalline powder
Odor OdorlessMelting Point 142.5 ℃
Specific Rotation [α]D²⁵ (dry basis) -2.4° ~ -3.0°
Solubility Highly soluble in water; soluble in methanol; insoluble in acetone, ethyl acetate
Hygroscopicity Strongly hygroscopic (critical difference vs 50% mannitol blended grade)
pH (10% aqueous solution) 4.5 ~ 7.0Stability Unstable under high temperature & high humidity; requires nitrogen protection
2. Quality Specification (≥99.0% on anhydrous basis, HPLC)
| Test Item | Specification | Test Method |
|---|---|---|
| Assay (L-α-Glycerylphosphorylcholine) | ≥99.0% | HPLC |
| Water Content | ≤1.0% | Karl Fischer |
| Residue on Ignition | ≤0.5% | / |
| Related Substances (Total Impurity) | ≤1.0% | HPLC |
| β-Glycerylphosphorylcholine | Not detected | HPLC |
| D-α-Glycerylphosphorylcholine | ≤0.05% | HPLC |
| Heavy Metals (Pb) | ≤10 ppm | AAS |
| Arsenic (As) | ≤2 ppm | AAS |
| Total Plate Count | ≤1000 cfu/g | USP |
| Yeast & Mold | ≤100 cfu/g | USP |
| E. coli, Salmonella, S. aureus | Negative /25g | USP |
3. Application & Use
Pharmaceutical API: Raw material for choline alfoscerate injection and tablets for cerebrovascular & cognitive disorders
High-end Nootropic / Premium dietary supplement: High purity brain health raw material
Biochemical reagent & cell culture additive
Note: This is pure active powder, not diluted with mannitol like Alpha-GPC 50%.
4. Packing
Standard: 25kg fiber drum with inner nitrogen-sealed aluminum foil bag
Small package: 1kg / 5kg nitrogen-filled aluminum foil bag
Must be hermetically sealed to prevent moisture absorption
5. Storage & Transportation
Storage: Store at -20℃ ~ 5℃, tightly sealed, dry and dark warehouse, strictly avoid moisture and heat. Shelf life: 24 months under proper storage
Transport: Non-hazardous goods. Prevent package breakage and moisture ingress
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