Basic Information of Kojic acid CAS 501-30-4 USP cosmetic grade
Product name: Kojic acid, also known as Qujunic acid
Chemical name: 5-hydroxy-2-hydroxymethyl-4H-pyran-4-one
Molecular formula: C6H6O4, molecular weight: 142.11
Appearance: White to off white crystalline powder
Melting point: 152-155 ℃
Solubility: Easily soluble in water, methanol, and ethanol; Slightly soluble in ether and chloroform; Insoluble in benzene
Preparation method: Microbial fermentation (sugar fermentation production by Aspergillus oryzae, etc.)
The core mechanism of action chelates copper ions, strongly inhibits tyrosinase activity, and blocks melanin production; Simultaneously possessing antioxidant and antibacterial abilities.
Specification quality of Kojic acid
| Test Item | Specification | Test Method |
|---|---|---|
| Appearance | White or off-white crystalline powder | Visual |
| Assay (HPLC) | ≥99.0 % | HPLC |
| Melting Range | 152 ℃ ~ 156 ℃ | Capillary |
| Loss on Drying | ≤ 0.5 % | 105 ℃, 2h |
| Residue on Ignition | ≤ 0.1 % | Gravimetry |
| Chloride (Cl⁻) | ≤ 50 ppm | Titration |
| Heavy Metals (as Pb) | ≤ 3 ppm | AAS |
| Arsenic (As) | ≤ 1 ppm | AAS |
| Iron (Fe) | ≤ 10 ppm | AAS |
| Solubility | Freely soluble in water, ethanol; slightly soluble in ether | Visual |
| Microbiological Index (Cosmetic Raw Material) | |
|---|---|
| Total Aerobic Bacteria | ≤1000 cfu/g |
| Yeast & Mould | ≤100 cfu/g |
| E. coli | Negative |
| Salmonella | Negative |
Main use (commonly used in foreign trade)
Cosmetics raw materials (maximum application)
Whitening and freckle removing raw materials, skin care cream, essence, cleaning products; Inhibit pigmentation; Can be paired with arbutin and VC derivatives.Domestic cosmetics regulations have restrictions on the concentration of additives.
Food industry
Food color protectants, antioxidant preservatives; Inhibit meat browning; Prevent nitrite from generating nitrosamines; Fresh fruits and vegetables.
It is also a key intermediate for the synthesis of maltol and ethyl maltol.
Pharmaceutical field
External skin preparation raw materials; Antibacterial and anti-inflammatory excipients; Biochemical reagents (for detecting trivalent iron ions).
Other
Plant growth regulators, agricultural fungicides, and fresh flower preservatives.Packing
1kg/aluminium bag, 25 kg fibre drum
Total 9 MT per 20ft container with pallets,12 MT without pallets.
Storage & Handling
Stored in cool and airy place; away from fire and heat; handle with care;no breakage, avoid leakage.
It is valid for 2 years under proper condition.
Please refer to MSDS for more information about Safety, Storage and Transportation.
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