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Ketoconazole is a white or almost white crystalline powder and it is practically insoluble in water, freely soluble in methylene chloride, soluble in methanol, sparingly soluble in alcohol. Ketoconazole is widely and effecitvely used to treat some skin disorder such as fungal infection.
Appearance White or almost white crystalline powder
Solubility Practically insoluble in water, freely soluble in methylene chloride, soluble in methanol,
sparingly soluble in alcohol.
Melting range,℃ 148.0~152.0
Specific Rotation, -1.0~+1.0
Loss on Drying, % ≤0.50
Heavy metals, % ≤0.002
Residue on ignition, % ≤0.10
Chromatographic purity, % ≤2.0
Residue Solvent, %
Dimethyl sulfoxide ≤0.5
Bacteria Not more than 10 per g
Mold & yeas None-detected
Ketoconazole is an effective imidazole drug, which is widely used for the treatment of fungal infection. Ketoconazole is mainly used to produce Ketoconazole cream for the protection and treatment of skin disorders.