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Isotretinoin
Best factory price of 13-cis-Retinoic acid from China suppliers

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  • Product Details

Buy high quality 13-cis-Retinoic acid from China suppliers,please contact TNJ chemical for details, our TNJ have more than 15 years in this line since 2001, our product can be use in Medicine areas, Cosmetic areas. For more help, please contact mails sales16@tnjchem.com

 

Isotretinoin, also known as 13-cis retinoic acid, is an oral pharmaceutical drug primarily used to treatsevere nodular acne. Rarely, it is also used to prevent certain skin cancers (squamous-cell carcinoma), and in the treatment of other cancers. It is used to treat harlequin-type ichthyosis, a usually lethal skin disease, and lamellar ichthyosis. It is a retinoid, meaning it is related to vitamin A, and is found in small quantities naturally in the body. Its isomer, tretinoin, is also an acne drug.


Specification

Description:               Yellow crystalline powder

Assay:                       98.0-102.0%

Standard:                  USP26/28,EP5


Application

Vitamin A class drugs. It can rapidly and strongly inhibit the cell proliferation and differentiation process of skin glands cells. It has a high effect on severe nodular cystic acne. This product has a high gastrointestinal absorption, but invalid for topical administration. 

Isotretinoin is an effective drug against acne. It takes effect on four processes of acne procedures, preventing the formation of acne lesions: inhibiting sebaceous secretion; inhibit the growth of acne bacillus; inhibiting sebaceous hyperplasia; anti-inflammatory effect. Isotretinoin has no affinity to Vitamin A acid receptors. 


It may also reduce the volume of the sebaceous glands, reducing the skin's DHT, down-regulate the expression of skin androgen receptor. Other possible mechanism includes reducing the hair follicle keratosis, antibacterial, anti-inflammatory effects and so on. 


Packing

1,2,5,10kg/Tin


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